Lizard tails regenerate to provide clues

How to understand lizards and regenerate their tails after being molted, may lead to the regeneration of muscles and nerves, scientists say. Researchers have determined that after triggering a new tissue growth, the lizard sacrifices its tail in order to escape the predator's genetic program. Gene sequencing technology was used to study the process of green chameleon lizards. According to Kenro, chief scientist professor at Arizona State University in the United States, "The lizards basically share genes as humans. Lizards are the most closely related animal appendages and are regenerative. We have found that they have turned on at least 326 genes, Particular areas of the regenerated tail, including genes involved in embryonic development, in response to hormone signals and wound healing.” Many other animals, including cockroaches, cockroaches and fish, can also regenerate their tails, and sometimes their limbs.
All use the so-called "Wnt pathway", which provides molecular signals needed to control stem cells in many tissues, including the brain, hair follicles, and blood vessels. However, lizards have found only patterns that are distributed throughout the tail tissue. "Regeneration is not an instant process," said the co-author, also from Arizona State University, said Elizabeth Hutchins. "In fact, the lizard's tail needs more than 60 days of regeneration. The lizard's cells grow into tissues at some positions along the tail, forming a complex regenerative structure."
Professor Kenro added: "Using next-generation technologies, the genes expressed in all regeneration sequences of the sequences, we have locked in what genes are needed to regenerate the mysteries of the lizard tail." Regeneration through genetic formulations is in lizards and then utilized In those same genes in human cells, it may regenerate new cartilage, muscle, and even spinal cord in the future."

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